Elyse Moritz: First Large-Scale Study on Combined Neonatal Alloimmune Neutropenia and Thrombocytopenia
Elyse Moritz, Researcher at Federal University of São Paulo, shared a post on LinkedIn, about a recent article by Leandra C. Nogueira-Silva et al., published in Transfusion Journal, adding:
”Fresh off the press, the first large-scale study documenting the concurrent occurrence of neonatal alloimmune neutropenia and thrombocytopenia (NAIN and FNAIT).
The findings explore the serological and molecular features of these immune-mediated syndromes and highlight the potential pathogenic role of maternal anti-HLA class I antibodies, even in the absence of detectable anti-HPA or anti-HNA antibodies – reinforcing the importance of including HLA testing in the diagnostic workup of neonatal cytopenias.”
Title: Concurrent neonatal alloimmune neutropenia and thrombocytopenia: Prevalence and antibody specificity and intensity in a large Brazilian cohort
Authors: Leandra C. Nogueira-Silva, José O. Bordin, Samira A. Abbas, Larissa B. Lopes, Akemi K. Chiba, Josefina A. P. Braga, Juliana O. Martins, Renato Cerqueira, Karen N. C. Ziza, Dante Mario Langhi Jr., Elyse Moritz
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