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April, 2026
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Heghine Khachatryan: When Bleeding Speaks – Think Beyond Gynecology
Apr 29, 2026, 15:04

Heghine Khachatryan: When Bleeding Speaks – Think Beyond Gynecology

Heghine Khachatryan, Editor-in-Chief of Hemostasis Today, Head of Hemophilia and Thrombosis Center at Yeolyan Hematology and Oncology Center, shared a post on LinkedIn:

“When Bleeding Speaks – Think Beyond Gynecology

Heavy menstrual bleeding is not just a symptom – it is a diagnostic signal.

Up to 24% of women with HMB may have von Willebrand disease, the most common inherited bleeding disorder – yet often missed.

Red Flags

  • Menorrhagia from menarche
  • Bleeding more than 7 days
  • Iron deficiency anemia
  • Postpartum/surgical bleeding

Family history

  • Not symptoms – diagnostic alarms
  • Think VWD When
  • Bleeding is disproportionate
  • Treatment response is poor
  • Multisite bleeding exists
  • Pregnancy is complicated

Approach

Don’t treat in silos

  • Hematology plus Gynecology
  • vWF testing (activity, antigen, FVIII)
  • Risk assessment before surgery/pregnancy

Treatment is equal to Mechanism minus Based

  • Hormonal therapy
  • Tranexamic acid
  • DDAVP / vWF concentrates

Core Message

  • Treating bleeding alone is equal to incomplete care
  • Identifying cause is equal to changing outcomes

Final Thought

Every unexplained bleeding in a woman deserves a hemostasis workup.

Because sometimes,

‘just a period’ is a missed diagnosis.”

Salih Ehsan, Chief Executive Officer at Kulsoom Society of hematology, shared Heghine Khachatryan’s post on LinkedIn, adding:

“During HMB, a history of multi site bleeding (gum bleeding, Epistaxis , injection site bruising, purpuric skin rashes) , history of recurrent mucocutaneous bleeding since childhood.

Family history of disproportionate bleeding ( in male and female also) are very helpful to suspect vWD.

Most common and under diagnosed bleeding disorder in Gynecology.

Even if a male child with hemophilia, always take a gynecology history from his mother also.”

Heghine Khachatryan

Other posts featuring Heghine Khachatryan and Salih Ehsan on Hemostasis Today.