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Intissar Haddiya: Can Low-Dose Rivaroxaban Improve Cardiovascular Outcomes in Patients with Advanced CKD?
Intissar Haddiya/LinkedIn
Jun 6, 2026, 17:37

Intissar Haddiya: Can Low-Dose Rivaroxaban Improve Cardiovascular Outcomes in Patients with Advanced CKD?

Intissar Haddiya, Professor of Nephrology at Faculty of Medicine and Pharmacy of Oujda Mohammed First University, shared a post on LinkedIn about a recent article by Raja Ramachandran et al., published in JAMA, adding:

“Low-Dose Rivaroxaban and Cardiovascular Events in Advanced Kidney Disease (Track_Trial)

Can low-dose rivaroxaban improve cardiovascular outcomes in patients with advanced CKD?

In the TRACK randomized trial (1458 patients with CKD stage 4–5, including those on dialysis):

  • No reduction in major cardiovascular events (HR 1.09; p=0.46)
  • Higher rates of major bleeding (8.8% vs 6.0%)
  • Low-dose rivaroxaban did not provide cardiovascular benefit and increased bleeding risk in this high-risk population.”

Title: Low-Dose Rivaroxaban and Cardiovascular Events in Advanced Kidney DiseaseThe TRACK Randomized Clinical Trial

Authors: Sunil V. Badve, Vlado Perkovic, Vivekanand Jha, Raja Ramachandran, Lily Mushahar, Jan Menne, An S. De Vriese, Patrick Rossignol, Adrien Flahault, Maha Al Ammari, Habib Skhiri, Michael Walsh, David Collister, Adrian Liew, Laurent Billot, Severine Bompoint, Anthony Devaux, Min Jun, Enmoore Lin, Aline Ramos da Cruz, Jeffrey T. Ha, John W. Eikelboom, Ahmed Shaman, Meg J. Jardine, Shilpanjali Jesudason, Muh Geot Wong, Craig S. Anderson, Amit X. Garg, Hiddo J. L. Heerspink, Helen Monaghan, Anushka Patel, Patrick B. Mark, David C. Wheeler, Jicheng Lv, Li Zuo, Helen Pilmore, Martin Gallagher

Intissar Haddiya

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Adrian Liew Adrien Flahault Ahmed Shaman Aline Ramos da Cruz Amit X. Garg An S. De Vriese Anthony Devaux Anushka Patel Craig S. Anderson David C. Wheeler David Collister Enmoore Lin Habib Skhiri Health Helen Monaghan Helen Pilmore Hematology Hemostasis Hemostasis News Hemostasis Today Hiddo J. L. Heerspink Intissar Haddiya Jan Menne Jeffrey T. Ha Jicheng Lv John W. Eikelboom Laurent Billot Li Zuo Lily Mushahar Maha Al Ammari Martin Gallagher Medicine Meg J. Jardine Michael Walsh Min Jun Muh Geot Wong Patrick B. Mark Patrick Rossignol Raja Ramachandran Severine Bompoint Shilpanjali Jesudason Sunil V. Badve Vivekanand Jha Vlado Perkovic
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