Jean Connors: Can Prothrombin Levels Improve Antiphospholipid Syndrome Risk Assessment?
Jean Connors, Chief of Cancer Hematology at Dana-Farber Cancer Institute, shared Journal of Thrombosis and Haemostasis (JTH)’s post on LinkedIn, adding:
“We need a functional assay to assay prothrombotic potential of aPL–this is getting closer to identifying the impact of these antibodies.”
Journal of Thrombosis and Haemostasis (JTH) shared a post on LinkedIn about a recent article by Maria Grazia Cattini et al., adding:
“Plasma prothrombin antigenic levels across thrombotic and hemorrhagic phenotypes in triple-positive antiphospholipid patients with anti-prothrombin antibodies
In antiphospholipid patients carrying anti-prothrombin antibodies, plasma prothrombin levels appear to set the balance between clotting and bleeding.
As antigenic prothrombin fell, the phenotype shifted from thrombotic toward hemorrhagic along a continuum.
Measuring prothrombin antigen in these high-risk patients could sharpen risk stratification and help guide whether to lean toward anticoagulation or caution.”
Title: Plasma prothrombin antigenic levels across thrombotic and hemorrhagic phenotypes in triple-positive antiphospholipid patients with antiprothrombin antibodies
Authors: Maria Grazia Cattini, Elena Pontara, Elisa Bison, Marta Tonello, Alida Linda Patrizia Caforio, Nicola Pozzi, Vittorio Pengo
Stay updated on all scientific advances with Hemostasis Today.
-
Sep 2, 2026, 18:26Strengthening Comprehensive Care for Inherited Bleeding Disorders in Ecuador – World Federation of Hemophilia
-
Sep 2, 2026, 18:24Zeeshan Ahmed Khattak: Managing Febrile Neutropenia in Hematology/Oncology and Transplant Patients
-
Sep 2, 2026, 18:22Mark Heyland: The Role of Thromboinflammation in Fracture Non-Union
-
Sep 2, 2026, 18:18Katie Gonzalez: Understanding the Hidden Risk of Inherited Thrombophilias
-
Sep 2, 2026, 18:14Beruni Narmada W: Rare Basal Vein of Rosenthal Thrombosis Presenting With Thalamic Haemorrhage
-
Sep 2, 2026, 18:03Omnia Ahmed: Effect of Hematocrit (HCT) on Coagulation Testing
-
Sep 2, 2026, 17:44John Thymis: Five E-Posters Presented at ESC Congress 2026 in Munich
-
Sep 2, 2026, 17:42Edward Lee Carter: In Antithrombotic Therapy, “More Protection” Can Become More Harm Surprisingly Quickly
-
Sep 2, 2026, 17:41Mohsin Raza: Why Is Anticoagulation Used During Hemodialysis?