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José Luis Neyro: E4 and DRSP Reduce Hirsutism While Showing Comparable Effects on Thrombin Generation
José Luis Neyro/X
Aug 15, 2026, 19:30

José Luis Neyro: E4 and DRSP Reduce Hirsutism While Showing Comparable Effects on Thrombin Generation

José Luis Neyro, Senior Consultant at Hospital Universitario Cruces, Professor of the International Master of Climacteric and Menopause at the University of Madrid, shared a post on X about a recent article by Panicha Chantrapanichkul et al., published in RPTH Journal, adding:

“E4 and DRSP and DRSP-only had comparable effects on thrombin generation and TM-mediated anticoagulation in women with PCOS.

Estetrol and Drospirenone reduced hirsutism, supporting its consideration as a treatment option for PCOS.”

Title: Effects of estetrol/drospirenone versus drospirenone-only on thrombin generation in women with polycystic ovary syndrome: a randomized, double-blind, controlled trial

Authors: Panicha Chantrapanichkul, Paveenutch Wiwatboworn, Manee Rattanachaiyanont, Prasong Tanmahasamut, Thanyarat Wongwananuruk, Wichapanun Surasang, Theera Ruchutrakool, Yingyong Chinthammitr, Bundarika Suwanawiboon, Tarinee Rungjirajittranon

José Luis Neyro

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Anticoagulation bleeding Blood Bundarika Suwanawiboon drospirenone DRSP E4 Estetrol Gynecology Health Hematology Hemostasis Hemostasis News Hemostasis Today hirsutism José Luis Neyro Manee Rattanachaiyanont Medicine Panicha Chantrapanichkul Paveenutch Wiwatboworn PCOS polycystic ovary syndrome Prasong Tanmahasamut Tarinee Rungjirajittranon Thanyarat Wongwananuruk Theera Ruchutrakool Thrombin Generation Wichapanun Surasang Yingyong Chinthammitr
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