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Kausik Ray: Phase 1 Trial Highlights Anti-Inflammatory Effects of Ruvonoflast
May 27, 2026, 04:40

Kausik Ray: Phase 1 Trial Highlights Anti-Inflammatory Effects of Ruvonoflast

Kausik Ray, Professor of Public Health at Imperial College London, Past President of European Atherosclerosis Society, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in JACC Journals, adding:

“Ruvonoflast reduced hsCRP in patients with elevated inflammatory risk.

We just published the phase 1 data.

Ongoing Phase 2 trials.”

Title: Anti-inflammatory effects of oral NLRP3 inhibition with ruvonoflast among individuals at elevated cardiovascular risk

Authors: Kausik K. Ray, Nicholas Clarke, Peter Thornton, Amy E. Miles, Zsofia Digby, Melanie J. Davies, Michelle Gorman, Bianca Mullen, Valérie Reader, Missy Magill, Hilary Johnstone, Cono Ariti, Naveed Sattar, Nikolaus Marx, Ann Marie Navar, Adrian F. Hernandez, Jyothis T. George, Alan P. Watt, Javed Butler, Paul M. Ridker

Kausik Ray: Phase 1 Trial Highlights Anti-Inflammatory Effects of Ruvonoflast

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