Leonardo Roever: New Perspectives on Thromboinflammation in Acute Ischemic Stroke
Leonardo Roever, CEO of Brazilian Evidence-Based Health Network, shared on LinkedIn about a recent article by Umberto Pensato et al, published in Stroke, adding:
”Thromboinflammation in Acute Ischemic Stroke: From Pathophysiological Challenges to Emerging Therapeutic Opportunities
Despite major advances in intravenous thrombolysis and endovascular thrombectomy, nearly half of patients with acute ischemic stroke fail to achieve functional recovery, even after technically successful recanalization.
The gap between recanalization and reperfusion—the mismatch between angiographic vessel opening and the restoration of tissue-level perfusion—has brought thromboinflammation (the pathological interplay between coagulation and innate immunity) to the forefront of stroke biology.
This review outlines key thromboinflammatory challenges—such as recanalization resistance, the no-reflow phenomenon, and reperfusion injury—and discusses the therapeutic opportunities emerging from this context.”
Title: Thromboinflammation in Acute Stroke: From Pathophysiological Challenges to Emerging Therapeutic Opportunities
Authors: Umberto Pensato, Tyler Henry, Andrew M. Demchuk, Giuseppina Caligiuri
Stay updated on all scientific advances with Hemostasis Today.
-
Sep 5, 2026, 02:35Balaji Balagani: Exploring Stable vs Unstable vs Complete Coronary Block
-
Sep 5, 2026, 02:28N. Mariana S. Vasquez: Warm vs Cold Autoimmune Hemolytic Anemia for USMLE/NBME Questions
-
Sep 4, 2026, 22:03Maeve Crowley: Haemophilia Treatment Over the Decades and Hope for the Future
-
Sep 4, 2026, 22:01Lama Skieker: Understanding Thrombocytopenia in Malaria
-
Sep 4, 2026, 22:00Hiten Patel: How an IVC Filter Helps Prevent Pulmonary Embolism
-
Sep 4, 2026, 21:54Gianluca Costamagna: Investigating the Link Between Cancer and Acute Ischemic Stroke
-
Sep 4, 2026, 21:50Ben Creagh-Brown: PRAGUE-26 and HI-PEITHO Similar Benefits With Important Differences
-
Sep 4, 2026, 21:48Jin-Xiong She: Homocysteine beyond Heart Disease – The Methylation-Mobility Connection
-
Sep 4, 2026, 21:44Aravind Palraj: Anemia of Chronic Inflammation is Not Just “Iron Deficiency”