Mazen A. Juratli: Platelet-Derived Extracellular Vesicles as Potential Predictors of Survival in Liver Cancer
Mazen A. Juratli, Professor and Senior Consultant in Visceral Surgery at the University Hospital Münster, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in OAE Journals, adding:
“New publication: Platelet-derived extracellular vesicles and post-ablation survival in HCC
Our prospective cohort study is now out in: Extracellular Vesicles and Circulating Nucleic Acids
We profiled plasma extracellular vesicles (EVs) in 53 patients (38 HCC) before and 1 h after microwave ablation, alongside cytokines and T-cell subsets.
Key findings:
HCC patients showed a distinct EV signature with liver cancer stem cell-associated markers (CD133, CD44, CD24).
Four platelet-adhesion EV markers (CD29, CD41b, CD42a, CD62P) were higher before ablation in HCC patients who later died.
Thank you to all co-authors!”
Title: Platelet-derived extracellular vesicles and post-ablation survival in hepatocellular carcinoma: a prospective cohort study
Authors: Thomas Vogl, Ibrahim Büdeyri, Wenyi Gu, Elsie Oppermann, Lisa Ysermann, Dhruvajyoti Roy, Nicola Pollmann, Nour-Eldin Nour-Eldin, Katrin Eichler, Benjamin Struecker, Michael Praktiknjo, Kerstin Menck, Jonel Trebicka, Andreas Pascher, Ruchi Bansal, Wolf Bechstein, Markus Zimmermann, Mazen Juratli

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