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Muhammad Aqib Faizan: New Evidence Supports Optimized Riociguat Use in Pulmonary Hypertension
Muhammad Aqib F./LinkedIn
Apr 28, 2026, 11:26

Muhammad Aqib Faizan: New Evidence Supports Optimized Riociguat Use in Pulmonary Hypertension

Muhammad Aqib Faizan, Clinical Intern at District Headquarter Hospital, MTI, DIKhan, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in Medicine, adding:

“Check out our systematic review and meta-analysis published in Medicine Journal.

Optimizing Riociguat Therapy for Pulmonary Hypertension: A Systematic Review and Meta-Analysis of Dose Variability, Safety, and Efficacy

I’m proud to have led this collaborative international research effort focused on improving outcomes in patients with pulmonary hypertension.

Key Findings:

  • Riociguat significantly improved 6-minute walk distance
  • Reduced mean pulmonary arterial pressure
  • Lowered pulmonary vascular resistance
  • Decreased NT-proBNP levels
  • The 2.5 mg three-times-daily dose showed the most consistent benefit

Our findings support personalized dosing strategies to optimize efficacy and safety in pulmonary hypertension management.

Grateful to all my co-authors and mentors for their dedication and teamwork throughout this journey.”

Title: Optimizing riociguat therapy for pulmonary hypertension: A systematic review and meta-analysis of dose variability, safety, and efficacy

Auhtors: Faizan Muhammad Aqib, Rehman Tooba, Malik Hurais, Hudaib Muhammad, Tahir Muhammad Abdullah, Ohri Gunvi, Bano Saher, Fatima Laveeza, Ahmed Syed Hassan, Karam Ayat ul, Ahmed Zuhair, Rehman Abdul, Rabbani Samra, Dandamudi Mrunalini, Mahmmoud Fadelallah Eljack Mohammed, Humayun Zainab

Muhammad Aqib Faizan: New Evidence Supports Optimized Riociguat Use in Pulmonary Hypertension

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Ahmed Syed Hassan Ahmed Zuhair Bano Saher bleeding disorders Dandamudi Mrunalini Faizan Muhammad Aqib Fatima Laveeza Health Hematology Hemostasis Hemostasis News Hemostasis Today Hudaib Muhammad Humayun Zainab Karam Ayat ul Mahmmoud Fadelallah Eljack Mohammed Malik Hurais Medicine Medicine Journal Muhammad Aqib Faizan Ohri Gunvi Pulmonary Hypertension Rabbani Samra Rehman Abdul Rehman Tooba Riociguat Tahir Muhammad Abdullah
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