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Paolo Zamboni: Chronic Cerebrospinal Venous Insufficiency Hypothesis in Multiple Sclerosis
Jul 21, 2026, 13:10

Paolo Zamboni: Chronic Cerebrospinal Venous Insufficiency Hypothesis in Multiple Sclerosis

Paolo Zamboni, Professor of Vascular Surgery at the University Hospital of Ferrara, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in Journal of Neurology, Neurosurgery and Psychiatry, adding:

“Today, my article ‘Chronic Cerebrospinal Venous Insufficiency in Patients with Multiple Sclerosis’ reached 1,000 citations.

It is not my most cited paper, but it is certainly the one that literally sparked a fierce scientific controversy.

Even today, when a young resident investigates the jugular veins using ECD in a patient with MS, they ask me, ‘Professor, how could they claim it wasn’t true?’ I reply, ‘That is part of modern medicine, too—a game of illusion designed to either create or deny scientific evidence.'”

Title: Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis

Authors: P Zamboni, R Galeotti, E Menegatti, A M Malagoni, G Tacconi, S Dall’Ara, I Bartolomei, F Salvi

Paolo Zamboni: Chronic Cerebrospinal Venous Insufficiency Hypothesis in Multiple Sclerosis

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