Partha Haldar: Tenecteplase vs Alteplase in Prosthetic Valve Thrombosis
Partha Haldar, Epidemiologist, Additional Professor at All India Institute of Medical Sciences, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in JAMA Cardiology, adding:
“Delighted to share that our collaborative work is published in JAMA Cardiology.
Tenecteplase vs Alteplase in Mechanical Prosthetic Heart Valve Thrombosis: The TENET Randomized Clinical Trial.
In this non-inferiority trial, we showed Tenecteplase may be a safe and effective alternative to Alteplase in patients presenting with obstructive PHVT.
As an epidemiologist I contributed to the study’s design strategy, statistical analysis plan, formal analysis, and interpretation.
Grateful to my cardiology colleagues, Prof. Gautam Sharma, the PI, and the co-authors for an excellent interdisciplinary collaboration.
Congratulations to the entire team.
Looking forward to more interdisciplinary research.”
Title: Tenecteplase vs Alteplase in Mechanical Prosthetic Heart Valve Thrombosis
The TENET Randomized Clinical Trial
Authors: Gautam Sharma, Krishna Prasad Akkineni, Nayani Makkar, Asmita Shukla, Partha Haldar, Devagourou Velayoudam, Kamal Kamal, Sanjeev Kumar, Nitish Naik, Ambuj Roy, Sandeep Singh, Sandeep Seth, Rohit Bhatia

Stay updated with Hemostasis Today.
-
Sep 20, 2026, 03:58Salih Ehsan: The Complexities of HbF and HbA2
-
Sep 20, 2026, 03:22The Voices of People Living With Bleeding Disorders – EHC
-
Sep 20, 2026, 01:18Sebastian Mafeld: Has 2026 Changed How We Treat Pulmonary Embolism?
-
Sep 20, 2026, 01:16Pall T. Onundarson: DOACs – Monitoring, Tailoring Dose and Identifying Problems
-
Sep 20, 2026, 01:15Thierry Fumeaux: From Efficacy to Effectiveness – The Value of Real-World Evidence
-
Sep 20, 2026, 01:14Said El Shamieh: VEGFA Genetic Variants and Bleeding Risk During Warfarin Therapy
-
Sep 20, 2026, 01:04Omar Danoun: Levetiracetam May Increase Thromboembolic Risk With DOACs
-
Sep 20, 2026, 01:02Mohamed Abo-Aly: Which Antiseizure Medication is Safest for Patients on DOACs?
-
Sep 20, 2026, 00:58Hamza Rafiq: How Does a Deep Vein Thrombosis Become a PE?