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February, 2026
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Ramy Abdelnaby: Exploring The Timing of Antiplatelet Administration In Minor Stroke Post-Thrombolysis
Feb 16, 2026, 13:40

Ramy Abdelnaby: Exploring The Timing of Antiplatelet Administration In Minor Stroke Post-Thrombolysis

Ramy Abdelnaby, Consultant Neurologist / Oberarzt at RWTH Aachen University Hospital, shared on LinkedIn about a recent article by Hui-Sheng Chen et al, published in European Heart Journal:

”Exploring the timing of antiplatelet administration in minor stroke post-thrombolysis, the EAST trial offers a comprehensive insight.

Conducted across multiple centers in China, this double-blind, randomized study evaluated the efficacy and safety of early antiplatelet treatment within 6 hours of intravenous thrombolysis in patients with mild neurological deficits.

Despite the high expectations, the trial concluded there’s no significant difference in achieving excellent functional outcomes at 90 days between the early treatment group and placebo.

This challenges existing paradigms and emphasizes the need for cautious decision-making in early antiplatelet therapy.”

Title: Early antiplatelet treatment for minor stroke following thrombolysis: the EAST trial

Authors: Hui-Sheng Chen, Yu Cui, Xiao-Qiu Li, Xin-Hong Wang, Chang-Hao Jiang, Jing Li, Zhi-Mei Yuan, Li-Wei Zhao, Nan Kong, Hai-Ning Mi, Jiang Lu, Hong Zhang, You-Jun Liu, Er-Qiang Wang, Yan Yang, Cheng-Guang Song, Yi Zhang, Shu-Yao Wang, Hong-Guo Dai, Yi Yang, Shi-Mei Geng, Rong Yin, Duo-Lao Wang, Thanh N. Nguyen

Read the Full Article on European Heart Journal

Ramy Abdelnaby: Exploring The Timing of Antiplatelet Administration In Minor Stroke Post-Thrombolysis

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