Rebecca Mellema: Journal Club Spotlight on Layilin and Platelet Hyperactivation in Inflammatory Bowel Disease
Rebecca Mellema, Freelance Science Communicator, shared a post on LinkedIn:
“New Journal Club video!
This time, we’ll be visiting my own paper: “Layilin inhibits integrin activation, and its loss results in platelet hyperactivation via Rac1 in inflammatory bowel disease.”
Authors: Mellema RA, Queisser KA, Ajanel A, Albtoush N, Smith-Sanchez L, Rondina MT, Will J, Valentine JF, Petrey AC.
Due to issues with Adobe Premier (and not wanting to waste all my footage), I had to split my video into 2 parts as well as delete some content, such as brief summaries of the experiments I like to have at the video intro. I apologize for that! It’s not my intention to cut out such a crucial part! (But I also had to stop my computer from crashing)”
Proceed to the videos (part one, part two) attached to the post.
Title: Layilin inhibits integrin activation, and its loss results in platelet hyperactivation via Rac1 in inflammatory bowel disease
Authors: Rebecca A. Mellema, Kimberly A. Queisser, Abigail Ajanel, Nansy Albtoush, Lydia Smith-Sanchez, Matthew T. Rondina, Julie Will, John F. Valentine, Aaron C. Petrey
Read the Full Article on Blood

Stay updated on all scientific advances with Hemostasis Today.
-
Jun 23, 2026, 23:05Rounak Dubey: ISBT Academy Session on Agentic AI
-
Jun 23, 2026, 22:59Mohammed Maher Babiker: When ‘Low Platelets’ aren’t Really Low
-
Jun 23, 2026, 22:49Giovanni Merlino: Why Does Stress Hyperglycemia Worsen Stroke Outcomes?
-
Jun 23, 2026, 22:41Tareq Abadl: Coombs Test – The Key to Detecting Immune-Mediated Hemolysis
-
Jun 23, 2026, 22:32How WFH Impacted the Bleeding Disorders Community in 2025
-
Jun 23, 2026, 22:03Erin VanDyke: A Journey Through VTE Leadership and Healthcare Transformation
-
Jun 23, 2026, 21:19Ahmed Koriesh: Join Us for Future of Stroke Care 2026
-
Jun 23, 2026, 20:30Aladdin Mohammad: Baseline IgG as a Key Predictor of Hypogammaglobulinaemia in AAV
-
Jun 23, 2026, 19:20Simos Kokkovos: 1st Ever Mobile Stroke Unit in Greece is on its way to Metropolitan Hospital