Siddarth Raajasekar on Neopterin Association with Stroke and Carotid Endarterectomy
Siddarth Raajasekar, Principal Investigator at The Vital Lab, shared on LinkedIn:
”I am pleased to share that my latest research article has been published in Pteridines (De Gruyter Brill).
Title: Plasma total neopterin and neopterin levels are significantly elevated in stroke patients before carotid endarterectomy surgery
DOI: 10.1515/pteridines-2025-0055
This study provides new clinical evidence linking macrophage-driven inflammatory metabolites—neopterin and total neopterin—to vascular risk in patients undergoing carotid endarterectomy.
It reinforces the translational relevance of immune-redox biomarkers in cerebrovascular disease.
Grateful to my collaborators, mentors, and institutional support for enabling this work.
I look forward to expanding this line of research through the VITAL Lab with upcoming multicentric clinical and computational studies.”
Read the full article here.
Article: Plasma total neopterin and neopterin levels are significantly elevated in stroke patients before carotid endarterectomy surgery
Authors: Siddarth Raajasekar, Justin Roake, Vicky Cameron, Ruth Benson, Anna Pilbrow, Steven Gieseg

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