Tahereh Yavari — Anticoagulation in Behçet’s Syndrome: Revisiting an Ongoing Debate
Tahereh Yavari, Rheumatology fellowship at Tehran University of Medical Sciences (TUMS), shared a post on LinkedIn:
“Anticoagulation in Behçet’s Syndrome — A Fresh Perspective
The role of anticoagulation in Behçet’s syndrome remains one of the most debated questions in rheumatology.
A recent correspondence by Serhat Erol et al. in Nature Reviews Rheumatology (2025) revisits this topic with new insights.
Their findings suggest that adding anticoagulants to immunosuppressive therapy can significantly reduce venous thrombosis recurrence compared with immunosuppression alone.
The authors emphasize the concept of “thromboinflammation” — where inflammation and coagulation amplify each other.
Targeting both pathways might therefore provide additional benefit in selected patients.
Clinical message:
While immunosuppressive therapy remains the mainstay, adjunctive anticoagulation could be considered for patients with recurrent thrombosis — but only with careful risk assessment and multidisciplinary supervision.
This paper highlights the urgent need for well-designed randomized studies to guide practice in this complex area.
Reference:
Erol S. et al. Potential benefit of anticoagulation in Behçet syndrome.
Nature Reviews Rheumatology (2025).”
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