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Yasmin Mohtasham Kia: Anticoagulation Knowledge and Treatment Outcomes in Patients With Mechanical Heart Valves
Yasmin Mohtasham Kia/LinkedIn
Nov 14, 2026, 12:47

Yasmin Mohtasham Kia: Anticoagulation Knowledge and Treatment Outcomes in Patients With Mechanical Heart Valves

Yasmin Mohtasham Kia, Physician, Researcher at Rajaie Cardiovascular Research Center, posted on LinkedIn about a recent article she and her colleagues co-authored, published in BMC, adding:

“I’m pleased to share our recent study published in BMC Cardiovascular Disorders!

For patients with mechanical heart valves, lifelong warfarin therapy requires careful monitoring.

But how well do patients understand their treatment, and how does this knowledge relate to adherence, quality of life, and clinical outcomes?

In our study of 198 patients, we assessed anticoagulation knowledge (AKA), medication adherence (MMAS 8), and health related quality of life (EQ 5D 5L), alongside anticoagulation control (TTR) and major clinical outcomes.

Using Rasch analysis and Item Response Theory (IRT), we evaluated the psychometric properties of the Persian AKA questionnaire, identifying acceptable item fit but suboptimal item person targeting.

We also employed multivariable regression and Firth penalized logistic regression to investigate associations with clinical outcomes.

Our key findings:

  • Only 3.5 percent demonstrated adequate anticoagulation knowledge.
  • Higher educational attainment was significantly associated with better knowledge.
  • Medication adherence was predominantly moderate (80.4 percent), while the median EQ 5D 5L quality of life index was 0.74.
  • No clear association was established between anticoagulation knowledge and TTR or major clinical outcomes.

These findings underscore the need for more precise knowledge assessment tools and culturally tailored educational interventions.

I’m deeply grateful to Parham Sadeghipour for his invaluable mentorship, guidance, and continuous support throughout this research.

My sincere thanks also go to all my co authors for their contributions.”

Title: Anticoagulation knowledge assessment among patients with mechanical prosthetic heart valves attending a tertiary care hospital outpatient clinic

Authors: Yasmin Mohtasham Kia, Navid Fereidani, Yeganeh Pasebani, Zahra Haghighi Fashi, Arezo Hafezi Birgani, Melody Farrashi, Somayyeh Barati, Hooman Bakhshandeh, Parham SadeghipourYasmin Mohtasham Kia: Anticoagulation Knowledge and Treatment Outcomes in Patients With Mechanical Heart Valves

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Arezo Hafezi Birgani Health Hematology Hemostasis Hemostasis News Hemostasis Today Hooman Bakhshandeh Medicine Melody Farrashi Navid Fereidani Parham Sadeghipour Somayyeh Barati Yasmin Mohtasham Kia Yeganeh Pasebani Zahra Haghighi Fashi
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