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Hinde El Otmani’s Team Explores Plasmin-Mediated Proteolysis of von Willebrand Factor in Acutely Ill Patients
Hinde El Otmani/ISTH
Oct 16, 2025, 04:37

Hinde El Otmani’s Team Explores Plasmin-Mediated Proteolysis of von Willebrand Factor in Acutely Ill Patients

RPTH Journal shared on LinkedIn:

”Elevated von Willebrand factor (VWF) is common in liver disease, but its regulation remains unclear.

The latest study from Hinde El Otmani explores how plasmin-mediated VWF cleavage may lead to microvascular changes in acutely ill patients.

Check it out here.

Co-authors: Ton Lisman, Coen Maas, Marilena Stamouli, Jelle Adelmeijer”

Read the full article in RPTH.

Article: Plasmin-mediated proteolysis of von Willebrand factor in patients with acute and chronic liver disease

Authors: Hinde El Otmani, Marilena Stamouli, Jelle Adelmeijer, William Bernal, Coen Maas, Vishal C. Patel, Ton Lisman

Hinde El Otmani's Team Explores Plasmin-Mediated Proteolysis of von Willebrand Factor in Acutely Ill Patients

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acute liver disease chronic liver disease Coen Maas Hinde El Otmani Jelle Adelmeijer Marilena Stamouli Plasmin proteolysis rpth Ton Lisman Vishal C. Patel VWD VWF William Bernal
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