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Michael Hadley: Well-Timed ACC Statement Just Out in JACC Journals
Michael Hadley/LinkedIn
Dec 18, 2025, 15:23

Michael Hadley: Well-Timed ACC Statement Just Out in JACC Journals

Michael Hadley, System Director of Advanced Cardiac Imaging at Northwell Health, shared on LinkedIn:

”Well-timed ACC Statement just out in JACC Journals on reporting Quantitative Coronary Plaque Analysis (QCPA)

Key takeaways:

  • Use QCPA only when visual plaque is present to enhance risk assessment and guide initiation or intensification of preventive therapies
  • Required in reports (see figure): TPV, NCPV, CPV, qualitative statement about overall plaque, list of excluded segments, and comparison to any prior
  • To improve specificity, high-risk plaque is redefined as mild-moderate stenosis with both positive remodeling (>1.2x) and lipid-rich plaque (<70 HU)
  • Serial QCPA could be considered after 2-5+ years if it would change management, with plaque progression defined as ≥10-20mm3 of TPV or ≥5-10mm3 of NCPV
  • We need a shared validation dataset including IVUS/histology to evaluate the growing number or QCPA platforms

Bottom line: A strong first step toward standardized plaque reporting and building real trust in a tool built to personalize prevention.”

Read the full article here.

Article: Quantitative Coronary Plaque Analysis in Clinical Practice: 2025 ACC Scientific Statement

Michael Hadley: Well-Timed ACC Statement Just Out in JACC Journals

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ACC Coronary Plaque Health Hematology Hemostasis Hemostasis Today JACC Journals Medicine Michael Hadley QCPA thrombosis
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