Mamta Soni Shares Highlights from CBC Chennai 2026
Mamta Soni, Chief of Laboratory Services at Apollo Health and Lifestyle Limited, shared on LinkedIn:
”The first academic collaboration of 2026 began in Namma Chennai with a very well-attended CBC (Chennai Blood Club) meet today.
The meeting featured excellent interactive sessions, with the highlight being a challenging case of acquired haemophilia in an elderly patient on Hemlibra (emicizumab).
The discussion focused on how emicizumab interferes with routine clot based coagulation assays causing spurious shortening of APTT, falsely elevated Factor VIII levels, and unreliable Bethesda assays, making conventional monitoring of acquired hemophilia therapy almost impossible .
In patients on a Emicizumab, FVIII assays must be performed using bovine factors, two-step chromogenic methods.
Chromogenic FVIII assays provide accurate results in patients on emicizumab, whereas clot-based assays yield falsely normal values due to drug interference.
It gives me immense clinical satisfaction that we at the CRL Coagulation Laboratory were able to rapidly decode the puzzle, supporting both the clinician and, most importantly, the patient.
This case also strongly emphasized the critical importance of laboratories being aware of the patient’s clinical background and ongoing therapy before performing and interpreting coagulation tests.
Other stimulating cases discussed included:
* LAHPS syndrome (Lupus anticoagulant-hypoprothrombinemia syndrome )
* T-ALL: transplant decision-making using single-cell genomic data
* Renal amyloidosis spotter images
Overall, it was a rich clinical and academic feast, reinforcing the power of close clinician–laboratory collaboration.”
Stay updated with Hemostasis Today.
-
Sep 29, 2026, 19:00Caitlin Raymond: Can Artificial Blood Solve Blood Supply Shortages?
-
Sep 29, 2026, 18:51Chaza Alaji: Dyslipidemia, Thrombosis and the DIC Diagnostic Trap
-
Sep 29, 2026, 17:31Rajnikant Patel: Bridging Ayurvedic Concepts and Modern Toxin-Mediated Disease
-
Sep 29, 2026, 17:13Nicholas Lang։ A Meaningful Case of Immune Thrombocytopenia
-
Sep 29, 2026, 16:55Ayatullah Gamal Wahab: When the CBC Lies
-
Sep 29, 2026, 16:35Jonathan Douxfils: Navigating the VTE Risk Continuum in Reproductive Medicine
-
Sep 29, 2026, 16:35Chaima Rajeh: Types of Anemia and Their Laboratory Features
-
Sep 29, 2026, 16:27Scott Isaacs: How GLP-1 RAs Target Systemic Inflammation to Drive Cardio, Autoimmune, and Gut Health
-
Sep 29, 2026, 16:21Yitshak Kreiss: From Treating Patients to Defining the Standard of Knowledge