Ahmed Koriesh: Stroke Prevention in the New 2026 ACC/AHA Dyslipidemia Guideline
Ahmed Koriesh, Director of Hospital Neurology Service at Cleveland Clinic Florida, shared on LinkedIn:
”New 2026 ACC/AHA Dyslipidemia Guideline – What Neurologists Should Know
Stroke prevention is one of the areas most affected by the new lipid guidelines.
A few points stood out for neurologists:
- Lower LDL is Better
For patients with established ASCVD (including ischemic stroke), the guideline reinforces aggressive LDL lowering — most stroke patients would qualify for <55 mg/dL target.
- Earlier combination therapy
Rather than waiting months to escalate therapy, the guideline encourages earlier addition of ezetimibe or PCSK9 inhibitors when LDL targets are not reached.
- Lp (a) is gaining attention
Measurement of lipoprotein(a) is now recommended at least once in many patients to better define inherited cardiovascular and stroke risk.
- New lipid therapies are coming
Long-acting therapies targeting PCSK9 and emerging RNA-based treatments will help long-term lipid control in high-risk patients.
For neurologists, the guidelines leans towards more aggressive risk reduction.
For a clinical summary focused on stroke care.”
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