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X. Long Zheng: Novel Gain-of-Function ADAMTS13 Variant with Potential Therapeutic Impact
X. Long Zheng; Szumam Liu/www.kumc.edu
Mar 30, 2026, 15:18

X. Long Zheng: Novel Gain-of-Function ADAMTS13 Variant with Potential Therapeutic Impact

X. Long Zheng, Professor and Chair of Pathology and Laboratory Medicine at The University of Kansas, shared a post on LinkedIn about a recent article he and his colleagues co-authored, adding:

“Hot off the press in the Journal of Thrombosis and Haemostasis (JTH) from Szumam Liu et al. about a novel gain-of-funtion ADAMTS13 variant that may have therapeutic implications.

Thank you all for your hardworking and close collaboration.”

Title: ADAMTS13 R1206K Variant Exhibits an Open Conformation and Enhanced Proteolytic Activity toward von Willebrand factor

Authors: Szumam Liu, Xiaxin Dong, Quintijn Bonnez, Zhirong Chai, Chan Meng, Madison Gil, Karen Vanhoorelbeke, Konstantine Halkidis, X. Long Zheng

Read the Full Article on Journal of Thrombosis and Haemostasis

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ADAMTS13 Chan Meng Hematology Hemostasis Hemostasis News Hemostasis Today Journal of Thrombosis and Haemostasis JTH Karen Vanhoorelbeke Konstantine Halkidis Madison Gil Medicine Quintijn Bonnez Szumam Liu thrombosis Von Willebrand Factor X. Long Zheng Xiaxin Dong Zhirong Chai
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