X. Long Zheng: Novel Gain-of-Function ADAMTS13 Variant with Potential Therapeutic Impact
X. Long Zheng, Professor and Chair of Pathology and Laboratory Medicine at The University of Kansas, shared a post on LinkedIn about a recent article he and his colleagues co-authored, adding:
“Hot off the press in the Journal of Thrombosis and Haemostasis (JTH) from Szumam Liu et al. about a novel gain-of-funtion ADAMTS13 variant that may have therapeutic implications.
Thank you all for your hardworking and close collaboration.”
Title: ADAMTS13 R1206K Variant Exhibits an Open Conformation and Enhanced Proteolytic Activity toward von Willebrand factor
Authors: Szumam Liu, Xiaxin Dong, Quintijn Bonnez, Zhirong Chai, Chan Meng, Madison Gil, Karen Vanhoorelbeke, Konstantine Halkidis, X. Long Zheng
Read the Full Article on Journal of Thrombosis and Haemostasis
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