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Eric Topol: Is the Interferon Pathway a Key Driver of Inflammaging and Aging
Eric Topol/X
Apr 20, 2026, 10:59

Eric Topol: Is the Interferon Pathway a Key Driver of Inflammaging and Aging

Eric Topol, Founder and Director of Scripps Research Translational Institute, shared a post on X about a recent article by Zhaoli Liu et al., published in Cell Genomics:

“We’ve known inflammaging is a big part of why the human aging process accelerates.

Now the interferon pathway is invoked as having a causal role (via epigenetics) and potential for targeting.”

Title: Interferon-related inflammaging links epigenetic age acceleration to multimorbidity

Authors: Zhaoli Liu, Athanasios Ziogas, Yihan Zhang, Manoj Kumar Gupta, Konstantin Föhse, Esther Taks, Elisabeth Dulfer, Andrei Sarlea, Lorenzo Ventriglia, Büsra Geckin, Mohamad Ballan, Nienke van Unen, Leonie Helder, Stephanie Trittel, Peggy Riese, Simone Moorlag, Charlotte de Bree, Valerie Koeken, Vera Mourits, Martin Jaeger, Frank Pessler, Carlos A Guzmán, Leo AB Joosten, Yang Li, Cheng-Jian Xu, Mihai G Netea

Eric Topol: Is the Interferon Pathway a Key Driver of Inflammaging and Aging

Other posts featuring Eric Topol on Hemostasis Today.

Andrei Sarlea Athanasios Ziogas Büsra Geckin Carlos A Guzmán Cell Genomics Charlotte de Bree Cheng-Jian Xu Elisabeth Dulfer Eric Topol Esther Taks Frank Pessler Health Hematology Hemostasis Hemostasis News Hemostasis Today Inflammatory pathways Interferon Interferon-related inflammaging Konstantin Föhse Leo AB Joosten Leonie Helder Lorenzo Ventriglia Manoj Kumar Gupta Martin Jaeger Medicine Mihai G Netea Mohamad Ballan Nienke van Unen Peggy Riese Simone Moorlag Stephanie Trittel Valerie Koeken Vera Mourits Yang Li Yihan Zhang Zhaoli Liu
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