Eric Topol: Is the Interferon Pathway a Key Driver of Inflammaging and Aging
Eric Topol, Founder and Director of Scripps Research Translational Institute, shared a post on X about a recent article by Zhaoli Liu et al., published in Cell Genomics:
“We’ve known inflammaging is a big part of why the human aging process accelerates.
Now the interferon pathway is invoked as having a causal role (via epigenetics) and potential for targeting.”
Title: Interferon-related inflammaging links epigenetic age acceleration to multimorbidity
Authors: Zhaoli Liu, Athanasios Ziogas, Yihan Zhang, Manoj Kumar Gupta, Konstantin Föhse, Esther Taks, Elisabeth Dulfer, Andrei Sarlea, Lorenzo Ventriglia, Büsra Geckin, Mohamad Ballan, Nienke van Unen, Leonie Helder, Stephanie Trittel, Peggy Riese, Simone Moorlag, Charlotte de Bree, Valerie Koeken, Vera Mourits, Martin Jaeger, Frank Pessler, Carlos A Guzmán, Leo AB Joosten, Yang Li, Cheng-Jian Xu, Mihai G Netea
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