Rashad Mohamed: What Does ‘Capping’ Mean in Anticoagulant Dosing?
Rashad Mohamed, Icu Registrar at Imam Abdulrahman Al Faisal Hospital, shared a post on LinkedIn:
“What does ‘Cap’ mean in dosing?
In anticoagulation context (e.g.,Rashad Mohamed for PE):
Dose capping: putting a maximum fixed upper limit on the dose, even if the weight-based calculation gives a higher number.
Example: Patient weighs 180 kg 1 mg/kg results in 180 mg BID.
If someone ‘caps’ the dose at 150 mg results in patient receiving less than weight-based dose.
In morbid obesity, major guidance (e.g., International Society on Thrombosis and Haemostasis and American College of Chest Physicians) supports using actual body weight and does not recommend routine capping, unless there is a specific bleeding concern.
Why avoiding capping matters: Underdosing results in increased risk of treatment failure, increased risk of recurrent PE.”
Stay updated with Hemostasis Today.
-
Aug 14, 2026, 06:26Delivering Gene Therapy in Hemophilia – ISTH
-
Aug 13, 2026, 18:39Lukas Röthlisberger: Real-World Evidence on Effectiveness and Safety of Rivaroxaban in Children
-
Aug 13, 2026, 18:36Soner Yilmaz: Blood Safety in Türkiye Through More Than 22.5 Million Blood Donations
-
Aug 13, 2026, 18:31Muthukumarasamy Raja: FDA Approval of EZPLAZ Marks a Breakthrough in Emergency Plasma Care
-
Aug 13, 2026, 18:29Peter Zdziarski: Protecting Our Community While Creating a Future Where We Are No Longer Needed
-
Aug 13, 2026, 18:29Morgan E Amos: Thrilled to Receive the Student Research Award From HTRS
-
Aug 13, 2026, 16:38Sheharyar Raza: Plasma Exchange in Multiple Sclerosis
-
Aug 13, 2026, 16:31Juan Manuel Cisneros Carrasco: The True Cost of Blood Donation
-
Aug 13, 2026, 16:25Connie Montgomery: Bridging the Gap Between Patients, Culture and Clinical Trials