Vanessa Simioni Faria/Linkedin
Apr 26, 2026, 14:55
Vanessa Simioni Faria: Precision Anticoagulation and Expanding Donor Frontiers
Vanessa Simioni Faria, Postdoctoral Research Fellow Brigham and Women’s Hospital, shared a post on LinkedIn:
”ISHLT2026 – Day 3 Insights
From anticoagulation strategies in LVAD patients to redefining donor eligibility, the field is moving toward precision, safety, and smarter decision-making across the entire patient journey.
- SESSION 23 – Adverse Events Following Temporary and Durable Mechanical Circulatory Support in Adults
A few key highlights:
- Anticoagulation in HM3 – DOT-HM3 (1-year results)
Presented by Zuzana Tucanova, MD; the study explored DOAC use (apixaban) in HM3 patients BTT:
- In selected, stable patients, apixaban appears safe; however, there were higher rates of Blood transfusion, temporary MCS, renal replacement therapy, and longer hospital stays
A promising alternative to VKA; but caution is clearly warranted.
- Stroke and Preconditioning Strategies
- In a study presented by Yuriy Hrytsyna, preconditioning with transaxillary microaxial flow pump prior to durable LVAD implantation:
- Was NOT associated with increased postoperative stroke risk. Similar outcomes compared to no preconditioning.
SYMPOSIUM 34 – Taking Donor Expansion, Procurement, and Preservation to the Next Level
One of the presentations focused on pushing the boundaries of the donor pool: (presented by Dr. Ann Woolley)
- HIVplus Donors
A thought-provoking discussion highlighted that the barrier is no longer biological; but social, regulatory, and perceptual.”
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