Muhammad Aqib Faizan: New Evidence Supports Optimized Riociguat Use in Pulmonary Hypertension
Muhammad Aqib Faizan, Clinical Intern at District Headquarter Hospital, MTI, DIKhan, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in Medicine, adding:
“Check out our systematic review and meta-analysis published in Medicine Journal.
Optimizing Riociguat Therapy for Pulmonary Hypertension: A Systematic Review and Meta-Analysis of Dose Variability, Safety, and Efficacy
I’m proud to have led this collaborative international research effort focused on improving outcomes in patients with pulmonary hypertension.
Key Findings:
- Riociguat significantly improved 6-minute walk distance
- Reduced mean pulmonary arterial pressure
- Lowered pulmonary vascular resistance
- Decreased NT-proBNP levels
- The 2.5 mg three-times-daily dose showed the most consistent benefit
Our findings support personalized dosing strategies to optimize efficacy and safety in pulmonary hypertension management.
Grateful to all my co-authors and mentors for their dedication and teamwork throughout this journey.”
Title: Optimizing riociguat therapy for pulmonary hypertension: A systematic review and meta-analysis of dose variability, safety, and efficacy
Auhtors: Faizan Muhammad Aqib, Rehman Tooba, Malik Hurais, Hudaib Muhammad, Tahir Muhammad Abdullah, Ohri Gunvi, Bano Saher, Fatima Laveeza, Ahmed Syed Hassan, Karam Ayat ul, Ahmed Zuhair, Rehman Abdul, Rabbani Samra, Dandamudi Mrunalini, Mahmmoud Fadelallah Eljack Mohammed, Humayun Zainab
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