Maria Cherska: The Future of Familial Hypercholesterolemia Care
Maria Cherska, The head of cardiology department at The State Institution «V.P. Komisarenko Institute of Endocrinology and Metabolism», shared a post on LinkedIn about a recent article by Mohamad Warda et al., published in Lipids in Health and Disease։
”Familial Hypercholesterolemia (FH): Rethinking Detection and Long-Term Management – Insights from EAS 2025
Familial hypercholesterolemia remains substantially underdiagnosed worldwide, despite being a major driver of premature atherosclerotic cardiovascular disease. The gap between guideline recommendations and real-world implementation is still significant.
In this expert interview from EAS 2025, Prof. Gerald Watts discusses the evolving clinical strategy for FH management — from early identification and cascade screening to long-term LDL-C control and residual risk reduction.
Key clinical takeaways:
- Systematic early detection is critical
- Cascade screening should be integrated into routine practice
- Aggressive and sustained LDL-C lowering is essential
- Residual cardiovascular risk persists even after LDL-C reduction
FH is not a rare condition – it is a common, lifelong, high-risk state that requires proactive and structured management.
For cardiologists, lipidologists, endocrinologists, internists, and preventive cardiology specialists focused on high-risk patient care and long-term ASCVD prevention.
How do you currently implement cascade screening and long-term LDL-C control in FH patients?”
Title: Lipid rafts: novel therapeutic targets for metabolic, neurodegenerative, oncological, and cardiovascular diseases
Authors: Mohamad Warda, Samet Tekin, Mahmoud Gamal, Nagwa Khafaga, Fikret Çelebi, Giovanni Tarantino
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