Ali Saad Al-shammari: Exploring the Role of SGLT2 Inhibitors After TAVI
Ali Saad Al-shammari, Physician and Cardiology Researcher, shared a post on LinkedIn about recent article by Khadeeja Ali Hamzah et al., published in European Journal of Clinical Pharmacology, adding:
“Proud to share that our systematic review and meta-analysis has been published in the European Journal of Clinical Pharmacology:
‘Therapeutic impact of SGLT2 inhibitors following transcatheter aortic valve implantation:
a GRADE-assessed systematic review and meta-analysis.’
We conducted a PRISMA-guided review of four studies including 12,374 TAVI patients, comparing SGLT2 inhibitors with standard care.
SGLT2 inhibitor therapy was associated with lower:
All-cause mortality: RR 0.62
HF hospitalization: RR 0.67
Myocardial infarction: RR 0.83
Bleeding events: RR 0.81
No significant differences were observed for cardiac death, stroke, pacemaker implantation, or AKI.
While these findings suggest a promising role for SGLT2 inhibitors after TAVI, the evidence remains limited and largely observational. Further randomized trials are needed.
Grateful to all co-authors khadeeja ali, Yousif Kurmasha, Mohammedsadeq A. Shweliya, Muhammad Shahzaib, Atef Akoum their collaboration.”
Title: Therapeutic impact of SGLT2 inhibitors following transcatheter aortic valve implantation: a grade-assessed systematic review and meta-analysis
Authors: Khadeeja Ali Hamzah, Yousif Hameed Kurmasha, Ali Saad Al-Shammari, Mohammedsadeq A Shweliya, Ali Alsajad Hussein Al-Janabi, Muhammad Shahzaib, Atef Akoum, Yasar Sattar
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