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Jae Hyun Byun: Spatial Transcriptomics and the Emerging Complexity of Plaque Vulnerability
Jae Hyun Byun/ LinkedIn
May 22, 2026, 07:46

Jae Hyun Byun: Spatial Transcriptomics and the Emerging Complexity of Plaque Vulnerability

Jae Hyun Byun, PhD Doctoral Research Trainee at Vascular Health Unit, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in ATVB, adding:

“We’re proud to share our latest publication in Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB)!

By integrating CosMx spatial transcriptomics at single-cell and subcellular resolution, we challenge the idea that carotid plaque instability follows a single, uniform biology, but instead, may manifest differently between males and females.

A big thank you to the Vascular Health Unit and my supervisor Stella S. Daskalopoulou, the Bruker Spatial Biology team (Joe Beechem), the McGill Genome Centre (Ioannis (Jiannis) Ragoussis), and the RI-MUHC histopathology platform (Fazila C.) for their support and guidance!”

Title: Single-Cell Spatial Transcriptomics Reveals Sex-Specific Differences Driving Carotid Atherosclerotic Plaque Instability

Authors: Jae Hyun Byun, Helena Papacostas Quintanilla, Karina Gasbarrino, Ioanna Gianopoulos, Ashot S. Harutyunyan, Spyros Oikonomopoulos, John P. Veinot, Huaien Zheng, Jiannis Ragoussis, Stella S. Daskalopoulou

Jae Hyun Byun: Spatial Transcriptomics and the Emerging Complexity of Plaque Vulnerability

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Arteriosclerosis Ashot S. Harutyunyan ATVB Health Helena Papacostas Quintanilla Hematology Hemostasis Hemostasis News Hemostasis Today Huaien Zheng Ioanna Gianopoulos Jae Hyun Byun Jiannis Ragoussis John P. Veinot Karina Gasbarrino Medicine Spyros Oikonomopoulos Stella S. Daskalopoulou
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