Jeremiah Bernier-Latmani: Could Angpt2 Blockade Become a New Treatment for GI Bleeding in VWD
Jeremiah Bernier-Latmani, Senior Researcher at University of Lausanne, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in Blood:
“New paper in Blood from Anna Randi, Adela Constantinescu-Bercu and team showing that VWF deficiency drives abnormal blood vessel growth and bleeding in the gut by increasing Angpt2 levels – and that blocking Angpt2 could be a promising new treatment for GI bleeding in von Willebrand disease patients.
Bonus: I of course love to see their cover image of intestinal villi!
Delighted to have contributed to this work!”
Title: Von Willebrand factor deficiency impairs angiogenesis via angiopoietin-2: relevance for gut angiodysplasia
Authors:Adela Constantinescu-Bercu, Koval E Smith, Shuo Yi Wong, Mattia Ballerini, Alessia Nastro, Benjamin G Wiggins, Daniela Pirri, Yucheng Li, Juun Evers, Olga Tsiamita, Matthew Dibble, Charis Pericleous, Koralia Paschalaki, Graeme M Birdsey, Jeremiah Bernier-Latmani, Tatiana V Petrova, Michael A Laffan, Suthesh Sivapalaratnam, Marco Rasponi, Anna M Randi
Stay updated with Hemostasis Today.
-
Jul 12, 2026, 12:30Reduced-Dose DOACs in GI Malignancies: Toward Personalized Anticoagulation
-
Jul 12, 2026, 08:50Where the Hemophilia Community Comes Together at ISTH 2026 – EAHAD
-
Jul 12, 2026, 08:2210 Posts Not To Miss from ISTH 2026, Part 1
-
Jul 12, 2026, 07:58Brian O Mahony: Could NXT-007 Minimize the Need for Perioperative FVIII
-
Jul 12, 2026, 07:50Shayan Mohammadmoradi: Connecting the Next Generation of Hemostasis Researchers at ISTH 2026
-
Jul 12, 2026, 07:42Alexandra Yakusheva: ThrombInnov Debuts at ISTH 2026 with a Focus on Translational Research
-
Jul 12, 2026, 07:34Wolfgang Miesbach: ISTH 2026 Explores the Next Generation of APS Diagnostics
-
Jul 12, 2026, 07:28Sara Zalghout: ISTH 2026 Highlights Progress in Thromboinflammation Research
-
Jul 12, 2026, 07:13Ekaterina Balaian: Finding Healing Through Art at ISTH 2026