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Zeyad Kholeif: New Publication on Rapid Plaque Progression Leading to STEMI in a Young Athlete
Zeyad Kholeif/LinkedIn
May 28, 2026, 17:39

Zeyad Kholeif: New Publication on Rapid Plaque Progression Leading to STEMI in a Young Athlete

Zeyad Kholeif, Resident Doctor at Baptist Hospitals of Southeast Texas Internal Medicine Residency, Research Scholar at Mayo Clinic, shared a post on LinkedIn about a recent article he and his colleges co-authored, published in JACC: Case Reports, adding:

“Excited to share our latest publication in JACC: Case Reports:

‘From Nonobstructive Plaque to LAD Thrombosis in a 26-Year-Old Athlete’

  • 26-year-old bodybuilder
  • Heavy anabolic steroid with energy drink use
  • Initial angiography: nonobstructive LAD plaque
  • Weeks later: acute thrombotic LAD occlusion causing anterior STEMI

An important reminder that:

  • MINOCA is not always benign
  • Nonobstructive plaque can rapidly evolve into catastrophic coronary thrombosis
  • Toxic exposures may dramatically accelerate endothelial injury and plaque instability in young adults

Grateful for all the hard work done by my Co-residents and constant support from my residency program.”

Title: From Nonobstructive Plaque to LAD Thrombosis in a 26-Year-Old Athlete

Authors: Mohammad Abu Zalam, Zeyad Kholeif, Usama Afzaal, Mustafa Dilawar Khan, Rahul Patri

Zeyad Kholeif

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acute thrombotic LAD occlusion Anabolic Steroid Angiography Blood Cardiology Health Hematology Hemostasis News Hemostasis Today JACC Case Reports LAD LAD Thrombosis Medicine MINOCA Mohammad Abu Zalam Mustafa Dilawar Khan Nonobstructive Plaque Rahul Patri STEMI thrombosis Usama Afzaal Zeyad Kholeif
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