William Aird/X
Jul 7, 2026, 20:59
William Aird: An Unlucky Turn Into the Renal Artery
William Aird, Professor of Medicine at Harvard Medical School, shared a post on X:
“An unlucky turn (… into the renal artery)
Every red cell is on a road trip.
About 20% of cardiac output goes to the kidneys, so sooner or later many RBCs take the renal artery exit.
Bad luck.
Down in the renal medulla, the environment becomes intensely hypertonic.
The cell shrinks, concentrates, rehydrates, and keeps moving.
We draw red cells as static biconcave discs.
But their real life is dynamic: squeezing, deforming, exchanging water, crossing gradients, and surviving one hostile microenvironment after another.”

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