A Novel Peptide Strategy to Prevent Surface-Triggered Thrombosis – JTH
Journal of Thrombosis and Haemostasis (JTH) shared on LinkedIn about a recent article by Adam Hansen et al, adding:
”Peptide-mediated inhibition of surface-initiated thrombogenesis
A designed peptide, P12, blocked thrombus formation triggered by artificial surfaces while leaving normal clotting intact.
In testing, it curbed surface-initiated thrombogenesis without impairing physiological hemostasis.
The authors see translational promise for treating device-related thrombosis and for engineering antithrombotic surfaces and coatings that resist clotting without raising bleeding risk.”
Title: Peptide-mediated inhibition of surface-initiated thrombogenesis
Authors: Adam Hansen, Bernard Essuman, Georgios Kementzidis, Nabila Jaman Tripti, Fubao Lin, Volodymyr Chernyshenko, Richard A.F. Clark, Yuefan Deng, Miriam Rafailovich, Dennis Galanakis
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