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Michael Ombrello։ Decoding How Autoantibodies Cause Disease
Michael Ombrello/LinkedIn, Teerin Liewluck/LinkedIn
Jul 27, 2026, 17:14

Michael Ombrello։ Decoding How Autoantibodies Cause Disease

Michael Ombrello, Tenure-Track Investigator at National Institute of Arthritis and Musculoskeletal and Skin Diseases, shared Teerin Liewluck’s post on LinkedIn:
”Identifying autoantibodies is descriptive.

Identifying a new mechanism through which autoantibodies cause disease in an epitope-specific manner is revolutionary.

Congratulations to Iago Pinal-Fernandez, Andrew Mammen and colleagues!”

Teerin Liewluck, Professor of Neurology at Mayo Clinic Rochester, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in Annals of the Rheumatic Diseases, adding:

”Hot Off the Press:

Excited to be part of this outstanding collaborative work led by Iago Pinal-Fernandez and Andrew Mammen.

This paper provides important insights into one of the central questions in myositis:

How do myositis autoantibodies reach their target antigens and drive disease?

Congratulations to everyone involved in this exciting work!!!”

Title: Spatial transcriptomics reveals mechanism of autoimmunity driven by internalised autoantibodies

Authors: Iago Pinal-Fernandez, Katherine Pak, Maria Casal-Dominguez, Sandra Muñoz-Braceras, Gustaf Wigerblad, Stefania Dell’Orso, Faiza Naz, Shamima Islam, Gustavo Gutierrez-Cruz, Travis B. Kinder, S. Amara Ogbonnaya-Whittlesey, Andreu Fernández-Codina, Margherita Giannini, Benjamin Ellezam, Gilles Laverny, Valentine Gilbart, Océane Landon-Cardinal, Marie Hudson, Yves Troyanov, Davide Randazzo, Aster Kenea, Ana Matas-Garcia, Gloria Garrabou, Iban Aldecoa, Gabriela Ailen-Caballero, Albert Gil-Vila, Ernesto Trallero, Margherita Milone, Teerin Liewluck, Elie Naddaf, Gerard Espinosa, Carmen Pilar Simeon-Aznar, Alfredo Guillen-Del-Castillo, Corinna Preusse, Felix Kleefeld, Nikolas Bublitz, Werner Stenzel, Alain Meyer, Janet E. Pope, Albert Selva-O’Callaghan, Jose C Milisenda, Andrew L. Mammen.

Michael Ombrello։ Decoding How Autoantibodies Cause Disease

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Alain Meyer Albert Gil-Vila Albert Selva-O’Callaghan Alfredo Guillen-Del-Castillo Ana Matas-Garcia Andreu Fernández-Codina Andrew L. Mammen. Aster Kenea Benjamin Ellezam Carmen Pilar Simeon-Aznar Corinna Preusse Davide Randazzo Elie Naddaf Ernesto Trallero Faiza Naz Felix Kleefeld Gabriela Ailen-Caballero Gerard Espinosa Gilles Laverny Gloria Garrabou Gustaf Wigerblad Gustavo Gutierrez-Cruz Health Hematology Hemostasis Hemostasis News Hemostasis Today Iago Pinal-Fernandez Iban Aldecoa Janet E. Pope Jose C Milisenda Katherine Pak Margherita Giannini Margherita Milone Maria Casal-Dominguez Marie Hudson Medicine Michael Ombrello Nikolas Bublitz Océane Landon-Cardinal S. Amara Ogbonnaya-Whittlesey Sandra Muñoz-Braceras Shamima Islam Stefania Dell’Orso Teerin Liewluck thrombosis Travis B. Kinder Valentine Gilbart Werner Stenzel Yves Troyanov
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