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François Saller: TFPI-Targeting VHHs for Haemophilia and Rare Bleeding Disorders
François Saller/LinkedIn
Jul 29, 2026, 14:46

François Saller: TFPI-Targeting VHHs for Haemophilia and Rare Bleeding Disorders

François Saller, Researcher in Hemostasis and Thrombosis at INSERM UMR-S1176, Assistant Professor in Hematology at Faculty of Pharmacy, Paris-Saclay University, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in Thrombosis and Haemostasis, adding:

“Having just recovered from The Cure at Nimes Festival, I can now mention that our paper on anti-TFPI VHHs for rebalancing hemostasis in hemophilia and other rare bleeding disorders had finally been published in Thromb Haemost Thrombosis Haemostasis.

This project was initiated and co-led by Peter Lenting.

It really took off when a synthetic library of llama-derived VHHs generated at HITh lab Inserm by Ivan Peyron was used to identify our first functionally relevant VHHs.

Many more to come ?

Thanks to all the other co-authors with a special attention to Claire Auditeau, Elsa Bianchini, and Pradtahna Saenjamsai and Andréa Ruty for their pugnacity.”

Title: Anti-TFPI Single-Domain Antibodies: Novel Rebalancing Therapies for Hemophilia and Other Rare Bleeding Disorders

Authors: Claire Auditeau, Elsa P. Bianchini, Ivan Peyron, Andréa Ruty, Pradtahna Saenjamsai, Mariem Khamari, Tilman M. Hackeng, Olivier Christophe , Cecile V. Denis, Delphine Borgel, Peter J. Lenting, FranÇois Saller

François Saller: TFPI-Targeting VHHs for Haemophilia and Rare Bleeding Disorders

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Andréa Ruty bleeding disorders Cécile V. Denis Claire Auditeau Delphine Borgel Elsa P. Bianchini François Saller Health Hematology Hemophilia Hemostasis Hemostasis News Hemostasis Today Ivan Peyron Mariem Khamari Olivier Christophe Peter J   Lenting Pradtahna Saenjamsai Tilman M. Hackeng
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