François Saller: TFPI-Targeting VHHs for Haemophilia and Rare Bleeding Disorders
François Saller, Researcher in Hemostasis and Thrombosis at INSERM UMR-S1176, Assistant Professor in Hematology at Faculty of Pharmacy, Paris-Saclay University, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in Thrombosis and Haemostasis, adding:
“Having just recovered from The Cure at Nimes Festival, I can now mention that our paper on anti-TFPI VHHs for rebalancing hemostasis in hemophilia and other rare bleeding disorders had finally been published in Thromb Haemost Thrombosis Haemostasis.
This project was initiated and co-led by Peter Lenting.
It really took off when a synthetic library of llama-derived VHHs generated at HITh lab Inserm by Ivan Peyron was used to identify our first functionally relevant VHHs.
Many more to come ?
Thanks to all the other co-authors with a special attention to Claire Auditeau, Elsa Bianchini, and Pradtahna Saenjamsai and Andréa Ruty for their pugnacity.”
Title: Anti-TFPI Single-Domain Antibodies: Novel Rebalancing Therapies for Hemophilia and Other Rare Bleeding Disorders
Authors: Claire Auditeau, Elsa P. Bianchini, Ivan Peyron, Andréa Ruty, Pradtahna Saenjamsai, Mariem Khamari, Tilman M. Hackeng, Olivier Christophe , Cecile V. Denis, Delphine Borgel, Peter J. Lenting, FranÇois Saller
Stay updated on all scientific advances with Hemostasis Today.
-
Jul 29, 2026, 17:41Seema Dawood: Difference Between CBC Smear Staining and Cell Counts Staining
-
Jul 29, 2026, 16:30Mostafa Faisal: Impact of DNMT3A and TET2 Mutations on Clotting and Bleeding in PV and ET
-
Jul 29, 2026, 16:01Gerardo Moscatelli: The Spike Protein Cascade – From Endothelial Binding to Vascular Collapse
-
Jul 29, 2026, 15:42Julie Cardoso: FDA Clears the First AI-Guided Ultrasound Software for Suspected DVT
-
Jul 29, 2026, 15:26Ahmad Alkhammash: Completing an Advanced Fellowship in Adult Thrombosis Medicine
-
Jul 29, 2026, 15:13Yara Mahmoud: The Molecular Basis in Hematology
-
Jul 29, 2026, 15:11Louisa Jorm: A New Era of Dynamic Cardiovascular Risk Assessment
-
Jul 29, 2026, 15:04Filippo Consonni: Treatment Strategies for Hematologic Immune Dysregulation in Inborn Errors of Immunity
-
Jul 29, 2026, 14:53Samer Alsaid: Warfarin Outcomes Reassessed Through COMBINE AF