William Aird/X
Aug 21, 2025, 15:08
Does Hypersplenism Cause Thrombocytopenia? Insights from William Aird
William Aird, Professor of Medicine at Harvard Medical School, shared a post on X:
“DOES HYPERSPLENISM CAUSE THROMBOCYTOPENIA?
YES!
Platelet mass (circulating + splenic) regulates TPO. In hypersplenism, sequestered platelets still count toward mass → no ↑TPO drive, but fewer platelets in circulation due to redistribution.”
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