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Qizhen Shi: Immune Regulation in Hemophilia—Insights from TFH/TFR
Aug 24, 2025, 08:35

Qizhen Shi: Immune Regulation in Hemophilia—Insights from TFH/TFR

Qizhen Shi, Professor at the Medical College of Wisconsin and Senior Investigator at Versiti Blood Research Institute, posted  on X:

”Our new paper is out in Blood!
“The TFH/TFR pathway in FVIII immune responses in mice”
1) TFR cells have a dual role in regulating anti-FVIII responses
2) TFH/TFR axis is key to inhibitor development in hemophilia A .”

Read the full article here.

Title: The T follicular helper/T follicular helper regulatory pathway in FVIII immune responses in mice

Authors: Weiqing Jing, Jocelyn A. Schroeder, Saurabh Kumar, Juan Chen, Yuanhua Cai, Lynn M. Malec, Alexander L. Dent, Weiguo Cui, Qizhen Shi

Qizhen Shi

 

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