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Ali Saad Al-shammari: LAAC vs Medical Therapy for Stroke Prevention in AF
Ali Saad Al-shammari/LinkedIn
Sep 12, 2026, 15:15

Ali Saad Al-shammari: LAAC vs Medical Therapy for Stroke Prevention in AF

Ali Saad Al-shammari, Physician and Cardiology Researcher, shared a post on LinkedIn about recent artircle he and his colleagues co-authored, published in Journal of Cardiovascular Electrophysiology, adding:

“Our latest paper in Journal of Cardiovascular Electrophysiology about LAAC vs Medical therapy for stroke prevention in AF.

LAAC and medical therapy showed similar efficacy.

We have reconstructed the Kaplan-Meier curve and performed trial sequential analysis (TSA).

TSA showed that no major outcome reached the required information size; further trials are needed.

Evidence reached only 1.62% and 0.88% of the required size for all-cause and cardiac mortality, respectively.

I hope this paper adds to the cardiology literature.”

Title: Left Atrial Appendage Closure Versus Medical Therapy in Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Authors: Ali Alsajad Hussein Al-Janabi, Ali Saad Al-Shammari, Ahmed W. Hageen, Abdullah Zeyad Hameed Al-Tuaama, Abdullah Muataz Taha Al-Ibraheem, Muhammad Shahzaib, Diya Rathi, Khadeeja Ali Hamzah, Mohammedsadeq A. shweliya, Yousif Hameed Kurmasha, Mohamed Wagdy, Marwan M. Refaat

Ali Saad Al-shammari

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Abdullah Muataz Taha Al-Ibraheem Abdullah Zeyad Hameed Al-Tuaama Ahmed W. Hageen Ali Alsajad Hussein Al-Janabi Ali Saad Al-Shammari Diya Rathi Health Hematology Hemostasis Hemostasis News Hemostasis Today Journal of Cardiovascular Electrophysiology Khadeeja Ali Hamzah LAAC Marwan M. Refaat Medicine Mohamed Wagdy Mohammedsadeq A. Shweliya Muhammad Shahzaib Yousif Hameed Kurmasha
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