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Ali Saad Al-shammari: LAAC vs Medical Therapy for Stroke Prevention in AF
Sep 12, 2026, 15:15

Ali Saad Al-shammari: LAAC vs Medical Therapy for Stroke Prevention in AF

Ali Saad Al-shammari, Physician and Cardiology Researcher, shared a post on LinkedIn about recent artircle he and his colleagues co-authored, published in Journal of Cardiovascular Electrophysiology, adding:

“Our latest paper in Journal of Cardiovascular Electrophysiology about LAAC vs Medical therapy for stroke prevention in AF.

LAAC and medical therapy showed similar efficacy.

We have reconstructed the Kaplan-Meier curve and performed trial sequential analysis (TSA).

TSA showed that no major outcome reached the required information size; further trials are needed.

Evidence reached only 1.62% and 0.88% of the required size for all-cause and cardiac mortality, respectively.

I hope this paper adds to the cardiology literature.”

Title: Left Atrial Appendage Closure Versus Medical Therapy in Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Authors: Ali Alsajad Hussein Al-Janabi, Ali Saad Al-Shammari, Ahmed W. Hageen, Abdullah Zeyad Hameed Al-Tuaama, Abdullah Muataz Taha Al-Ibraheem, Muhammad Shahzaib, Diya Rathi, Khadeeja Ali Hamzah, Mohammedsadeq A. shweliya, Yousif Hameed Kurmasha, Mohamed Wagdy, Marwan M. Refaat

Ali Saad Al-shammari

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