Azusa Nagao: The Evolving Burden of Haemophilia Prophylaxis
Azusa Nagao, Lecturer at Department of Hematology-Oncology, shared a post on LinkedIn about a recent article she and her colleagues co-authored, published in Haemophilia, adding:
“Our 5-year prospective data from ADVANCE Japan are now published!
Since 2020, prophylaxis has become less burdensome, with a significant reduction in weekly treatment frequency, largely reflecting the impact of emicizumab.
However, bleeding rates appear to have plateaued.
Even with modern prophylaxis, bleeding remains an important burden for adults with haemophilia.”
Title: Five-Year Longitudinal Changes in Treatment Strategies and Clinical Outcomes in Adults With Haemophilia: The ADVANCE Japan Cohort Study
Authors: Azusa Nagao, Akihiro Sawada, Takeshi Kanematsu, Naoya Yamasaki, Hideyuki Takedani, Masanori Nojima, Yukio Hiroi, Teruhisa Fujii, Nobuaki Suzuki, Tadashi Matsushita, Satoshi Higasa, Kagehiro Amano, Yushi Chikasawa
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