Zoltan Nagy: With All Eyes on Optogenetics Today, What Can It Do in Megakaryocytes and Platelets?
Zoltan Nagy, Emmy Noether Group Leader – Experimental Hematology at University Hospital Würzburg, shared a post on LinkedIn:
“With all eyes on optogenetics today, what can it do in megakaryocytes and platelets?
Work from the labs of Markus Bender and Shiqiang Gao shows that optogenetic control of Ca²⁺ signalling can regulate megakaryocyte polarization and platelet function.
An exciting direction for the field, with plenty more to explore.”
Title: Optogenetic induction of subcellular Ca2+ events in megakaryocytes and platelets using a highly Ca2+-conductive channelrhodopsin
Authors: Yujing Zhang, Jing Yu-Strzelczyk, Dmitri Sisario, Rebecca Holzapfel, Zoltan Nagy, Congfeng Xu, Chengxing Shen, Georg Nagel, Shiqiang Gao, Markus Bender
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