Johannes Gratz: Perioperative Care in Factor VII Deficiency – Treating the Patient, Not the Number
Johannes Gratz, Professor and Deputy Head of the Department of Anesthesiology and Intensive Care Medicine at Campus Benjamin Franklin, Charité – University Medicine Berlin, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in Thrombosis Research, adding:
“Now published open access in Thrombosis Research: How do we manage congenital factor VII deficiency in the perioperative setting at Charité – Universitätsmedizin Berlin?
The condition is rare, and robust evidence to guide perioperative care is equally scarce.
The key takeaway: While treatment decisions were primarily driven by FVII activity levels, bleeding events clustered in patients with mild deficiency undergoing high-risk procedures.
As so often, we should treat patients, not numbers.
Perioperative risk assessment should consider both the patients individual bleeding phenotype and the bleeding risk associated with the procedure.”
Title: Perioperative haemostatic management and bleeding outcomes in congenital factor VII deficiency: a retrospective cohort study
Authors: Friederike Töpper, Philipp Brandhorst, Thomas Dörner, Christoph Sucker, Ralf Hammerich, Christoph Dibiasi, Sascha Treskatsch, Johannes Gratz
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