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Carlos Esteban Gasko: Restrictive Transfusion in Critical Care

Carlos Esteban Gasko/LinkedIn

Nov 12, 2026, 10:13

Carlos Esteban Gasko: Restrictive Transfusion in Critical Care

Carlos Esteban Gasko, Senior Consultant of Intensive Care at Muhayil Assir General Hospital, shared a post on LinkedIn about an article by Paul Hébert et al., published in The New England Journal of Medicine, adding:

“TRICC (NEJM 1999): the trial that made 7 g/dL the transfusion threshold in the ICU.

838 euvolaemic critically ill adults in 25 Canadian ICUs were randomised to a restrictive strategy (transfuse below 7.0 g/dL, keep haemoglobin at 7.0–9.0) or a liberal strategy (transfuse below 10.0 g/dL, keep 10.0–12.0).

The restrictive group received 54% fewer red-cell units, and 33% were never transfused. 30-day mortality was 18.7% vs 23.3% (95% CI for the difference −0.84 to 10.2; P=0.11), hospital mortality 22.2% vs 28.1% (P=0.05), with fewer cardiac complications. TRISS, MINT and the 2023 AABB guideline came later. Swipe through the document.”

Title: A Multicenter, Randomized, Controlled Clinical Trial of Transfusion Requirements in Critical Care

Authors: Paul Hébert, George Wells, Morris Blajchman, John Marshall, Claudio Martin, Giuseppe Pagliarello, Martin Tweeddale, Irwin Schweitzer, Elizabeth Yetisir

Carlos Esteban Gasko: Restrictive Transfusion in Critical Care