Hemostasis Today
NewsFeed
Headlines Hematology Health Medicine VTE ASH Plasma Donation
July, 2026
July 2026
M T W T F S S
 12345
6789101112
13141516171819
20212223242526
2728293031  
Courtney Lawrence: The AABB Bulletin on Neonatal Red Blood Cell Transfusion and Mannitol Exposure is Now Released
Courtney Lawrence/LinkedIn
Jun 12, 2026, 15:16

Courtney Lawrence: The AABB Bulletin on Neonatal Red Blood Cell Transfusion and Mannitol Exposure is Now Released

Courtney Lawrence, Divisional Chief Medical Officer at the American Red Cross, shared a post on LinkedIn:

“The AABB Bulletin on Neonatal Red Blood Cell Transfusion and Mannitol Exposure is now released!

Key points:

  • Mannitol-containing RBC units are widely used globally and remain standard in many settings.
  • Evidence supports safety in routine small-volume neonatal transfusions (<20 mL/kg)..
  • For large-volume transfusions (>20 mL/kg), data are limited. Risk is not confirmed, but cannot be excluded, particularly with rapid transfusion or impaired patient renal function.
  • Potential clinical concerns (e.g., fluid shifts, electrolyte imbalance) are largely theoretical or extrapolated from therapeutic mannitol dosing, not transfusion-specific evidence.
  • Washing or volume reduction of red cell units may reduce exposure but come with other trade-offs (e.g., transfusion delays, RBC damage).

Take home:

  • Current evidence supports continued use of mannitol-containing RBCs for most neonatal transfusions, while emphasizing clinical judgment and caution in large-volume scenarios.
  • Urgent transfusions should not be delayed due to concerns about mannitol exposure.”

Courtney Lawrence: The AABB Bulletin on Neonatal Red Blood Cell Transfusion and Mannitol Exposure is Now Released

Stay updated featuring Courtney Lawrence on Hemostasis Today.

anemia bleeding bleeding disorders Blood Blood donation Courtney Lawrence Headlines Health Hematology Hemophilia Hemostasis Hemostasis News Hemostasis Today
NewsFeed