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Abeer Alanazi: Asundexian Reduces Stroke and Mortality Without Increased Bleeding
photo: ajmc.com
Feb 7, 2026, 15:24

Abeer Alanazi: Asundexian Reduces Stroke and Mortality Without Increased Bleeding

Abeer Alanazi, American Board Certified Pharmacotherapy Specialist and member at European Stroke Organisation (ESO), shared a post on LinkedIn.

“OCEANIC-STROKE

  • Patients with non-cardioembolic ischemic stroke or TIA
  • Concomitant dual antiplatelet therapy (DAPT)
  • Asundexian initiated within 72 hours of symptom onset
  • 6,162 patients received asundexian; 6,165 received placebo
  • Treatment duration: 3–31 months
  • 30% of patients had NIHSS >4

Efficacy

  •  Significant reduction in acute ischemic stroke (AIS)
  • Significant reduction in cardiovascular mortality
  •  Significant reduction in all-cause mortality

Treatment effects were consistent across the overall population and all prespecified subgroups throughout the treatment period.

Safety

  • No increase in major bleeding
  • No increase in non-major bleeding
  •  No increase in symptomatic intracranial hemorrhage (sICH)
  • No increase in hemorrhagic stroke
  •  No increase in fatal bleeding”

Abeer Alanazi: Asundexian Reduces Stroke and Mortality Without Increased Bleeding

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