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May 5, 2026, 08:20
Diana Domenica Bruno: New Perinatal Research on Sepsis as Redefining Maternal Risk
Diana Domenica Bruno, Chief Executive Officer at Una Vita, shared a post on LinkedIn:
“New Perinatal Research: Sepsis is Redefining Maternal Risk
Recent 2025–2026 findings are reshaping clinical priorities:
- Maternal sepsis is rising as a leading cause of morbidity and mortality. Delayed recognition – often masked by normal physiologic changes of pregnancy – remains the most preventable failure point.
- Placental pathology is central to infection‑related outcomes. New evidence links subclinical placental inflammation and vascular malperfusion with fetal compromise, stillbirth, and early‑onset neonatal sepsis.
- Early detection protocols are tightening. Updated research supports infection‑specific vital‑sign thresholds, rapid escalation pathways, and earlier initiation of broad‑spectrum coverage when sepsis is suspected.
- Neonatal sepsis trends demand closer surveillance. Rising early‑onset sepsis in preterm infants is strongly associated with maternal infection, prolonged rupture of membranes, and gaps in intrapartum prophylaxis.
Where data matters:
The Una Vita Perinatal Database provides real‑time visibility into infection patterns, placental findings, escalation timelines, and neonatal outcomes – giving leaders the actionable insight needed to strengthen sepsis pathways across the perinatal continuum.
Bottom Line:
Earlier infection recognition, faster escalation, and data‑driven sepsis surveillance are now essential to improving maternal and neonatal outcomes.”
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