Heghine Khachatryan: Endometriosis Is Not Only a Pain Disorder
Heghine Khachatryan, Editor-in-Chief of Hemostasis Today, Head of Hemophilia and Thrombosis Center at Yeolyan Hematology and Oncology Center, shared a post on LinkedIn:
”Endometriosis is not only a pain disorder.
It should increasingly be recognized as a systemic clinical condition, associated not only with chronic pelvic pain, dysmenorrhea, and infertility, but also with fatigue, significant impairment in quality of life, heavy menstrual bleeding, and iron deficiency.
Recent international evidence suggests that women with endometriosis are at increased risk of iron deficiency, and in many cases, low ferritin may be present even before overt anemia develops.
This requires a shift in our clinical thinking.
When a patient presents with:
- heavy menstrual bleeding
- pronounced fatigue
- pelvic pain
- subfertility
- and ‘borderline normal’ hemoglobin
we should not limit management to symptomatic pain control alone.
A comprehensive evaluation should include:
- ferritin levels
- complete blood count indices
- assessment of iron deficiency
- evaluation for abnormal uterine bleeding / adenomyosis overlap
- and the overall inflammatory and functional burden of disease
Modern management of endometriosis is multidimensional:
- early clinical suspicion
- targeted imaging
- individualized management of pain and bleeding
- timely identification and correction of iron deficiency
- and, when appropriate, consideration of newer therapeutic options, including oral GnRH antagonists in selected patients
The key message is clear:
Low ferritin in a woman with endometriosis is not a minor laboratory finding.
It may represent a clinically meaningful indicator of:
- ongoing blood loss
- disease burden
- and unrecognized functional compromise
Contemporary endometriosis care must go beyond lesion detection and focus on: iron status, bleeding burden, and the full impact on a woman’s daily life.”
Other posts featuring Heghine Khachatryan on Hemostasis Today.
-
Apr 14, 2026, 15:43Webinar on Aplastic Anemia Clinical Case – ASH
-
Apr 14, 2026, 15:36Alisha Tuck: Navigating the First Trimester with Ultrasound and Anticoagulation Management
-
Apr 14, 2026, 15:26Tijjani Balas: The End of ‘Type O Negative’ Shortages? – A New Era in Blood Transfusion
-
Apr 14, 2026, 15:07Carlos Henrique Del Carlo: HFpEF Reimagined as an Adipose Tissue Driven Disease
-
Apr 14, 2026, 15:05Matteo Foschi: ASPERA-R Study Reveals Competing Causes Of Breakthrough Stroke On Anticoagulation
-
Apr 14, 2026, 14:48Samwel Mikaye: From Virchow’s Triad to Prevention of PE in Patients with DVT
-
Apr 14, 2026, 14:43Chokri Ben Lamine: Diamond – Blackfan Anemia and Congenital Dyserythropoietic Anemia Pearls
-
Apr 14, 2026, 14:14From the Clinical Transfusion Working Party – 2025 International Platelet Transfusion Guidelines – ISBT
-
Apr 14, 2026, 13:48Antoine Francis: This Is What a Donation Actually Becomes