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From Gene Mutation to Clot Risk in Factor V Leiden – ICHCC
ICHCC/LinkedIn
May 2, 2026, 10:24

From Gene Mutation to Clot Risk in Factor V Leiden – ICHCC

Iranian Comprehensive Hemophilia Care Center shared a post on LinkedIn:

“Factor V Leiden (FVL):

  • is the most common inherited blood clotting disorder in populations of European descent, caused by a mutation in the \(F5\) gene. It makes blood more prone to clotting (thrombophilia) because the mutated Factor V protein resists inactivation by protein C.
  • While most carriers never experience a clot, it significantly increases the risk of deep vein thrombosis (DVT) and pulmonary embolism.”

From Gene Mutation to Clot Risk in Factor V Leiden - ICHCC

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