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Ihab Suliman: A Snake Venom Helping Diagnose an Autoimmune Clotting Disorder?
Aug 18, 2026, 19:32

Ihab Suliman: A Snake Venom Helping Diagnose an Autoimmune Clotting Disorder?

Ihab Suliman, JA Assistant Professor and Consultant Advanced Cardiac Imaging at King Abdulaziz Medical City, shared a post on X:

“A snake venom helping diagnose an autoimmune clotting disorder?

Medicine is wild.

Russell’s viper venom directly activates Factor X.

In the dRVVT test, the venom triggers clotting – but the reaction still needs phospholipid.

Enter Lupus Anticoagulant.

It interferes with phospholipid-dependent clotting, so:

dRVVT becomes prolonged

Then the lab adds excess phospholipid…

The clotting time shortens. That strongly supports Lupus Anticoagulant.

And here is the paradox:

  • In the lab, it looks like an anticoagulant
  • In the patient, it can cause dangerous thrombosis

Snake venom. Autoantibodies. Blood clots. One elegant diagnostic test.”

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