Irem Karaman Sebin/X
Oct 18, 2026, 00:07
Irem Karaman Sebin: The Evidence Favoring Warfarin in High-Risk Antiphospholipid Syndrome
Irem Karaman Sebin, Internal Medicine Resident at Florida International University – Herbert Wertheim College of Medicine, shared a post on X:
“Today I learned that antiphospholipid syndrome is the only major thrombophilia with randomized trial evidence favoring warfarin over DOACs, particularly in high-risk patients with arterial thrombosis, possibly due to inhibition of multiple vitamin K–dependent coagulation factors, although the mechanism remains unclear.”
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