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Mahesan Subramaniam: Higher Coffee Intake Linked to Younger Brain Age and Better Cognitive Performance
Dato Capt. Mahesan Subramaniam/LinkedIn
Feb 13, 2026, 14:56

Mahesan Subramaniam: Higher Coffee Intake Linked to Younger Brain Age and Better Cognitive Performance

Dato Capt. Mahesan Subramaniam, Co-Founder of United Health Tourism, shared a post on LinkedIn:

”According to a very recent study (December 2024), drinking more than five cups of coffee per day is associated with a 6.7 year reduction in brain age and enhanced cognitive performance.

  • The study found that people who drank more coffee actually scored much higher on cognitive tests, such as those measuring attention, processing speed and visuomotor coordination compared to those who drank less coffee.
  • The study also found that people who drank more coffee had lower levels of inflammatory markers, even when accounting for factors like age, sex and smoking.
  • The study’s authors suggest that coffee’s protective effect may be due to caffeine, magnesium, and Vitamin B3 and because it reduces inflammation.
  • The study also suggests that people with atrial fibrillation (AFib) who drink coffee may not need to be discouraged from doing so, as it may actually be beneficial for them. People with AFib are at a higher risk of mental decline and coffee may be able to help prevent or slow it.
  • Studies have also shown that higher coffee consumption is associated with slower cerebral AB-amyloid accumulation over time and a lower risk of developing Alzheimer’s Disease, and other forms of dementia.
  • In one study, participants who consumed two or fewer cups of coffee per day were more likely to develop dementia and Alzheimer’s Disease than those who consumed more.

In Alzheimer’s Disease, amyloid clumps together to form plaques that are toxic to the brain. Coffee reduces the accumulation of these plaques by reducing amyloid production and attenuating the neurotoxicity associated with them.

Some studies suggest that coffee’s compounds actually work synergistically with caffeine to produce these effects, more so than caffeine or decaffeinated coffee alone.

PMID: 34867277”

Mahesan Subramaniam: Higher Coffee Intake Linked to Younger Brain Age and Better Cognitive Performance

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