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First-Time Generalized Seizure and Headache – Case Report
Prof. Dr. Wilhelm Nacimiento/LinkedIn
Sep 28, 2025, 04:21

First-Time Generalized Seizure and Headache – Case Report

Neurovaskuläres Zentrum shared a post on LinkedIn:

“-A 52-year-old male patient presented due to a first-time generalized seizure and headache

-CCT revealed strong suspicion of thrombosis of a prominent cortical vein in the left frontotemporal region, particularly involving the Vein of Trolard and the Vein of Sylvius and their branches, indicated by pre-existing hyperdensity

-CTA showed an isolated occlusion of the left superficial superior anastomotic vein (Vein of Trolard), extending into the superficial middle cerebral vein (Vein of Sylvius) and into the sphenoparietal sinus

-The patient was admitted to the stroke unit and therapeutic anticoagulation was initiated using an aPTT-guided heparin infusion

-Over the course of hospitalization, there was clinical deterioration and worsening of headaches

-Imaging showed slight progression of the thrombosis

-Follow-up cMRI showed a localized diffusion restriction surrounding the thrombosis, indicating the onset of thrombus resorption. FLAIR sequences showed faint parieto-temporal and occipito-temporal hyperintensities, consistent with mild edema

-Overlapping anticoagulation therapy with warfarin (Marcoumar) was initiated

-At last follow-up, the patient still had mild aphasia with somewhat hesitant speech and fine motor impairment of the right hand.

Prof. Dr. Wilhelm Nacimiento Dr. med. Martin Schlunz-Hendann Prof. Dr. Martin Scholz”

First-Time Generalized Seizure and Headache - Case Report

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Case CCT CTA Dr. med. Martin Schlunz-Hendann Generalized Seizure Headache Neurovaskuläres Zentrum Prof. Dr. Martin Scholz Prof. Dr. Wilhelm Nacimiento Seizure Vein of Sylvius Vein of Trolard
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